Applications of Nanodiamonds in Drug Delivery and Catalysis

作者:Moosa Basem; Fhayli Karim; Li Song; Julfakyan Khatchatur; Ezzeddine Alaa; Khashab Niveen M*
来源:Journal of Nanoscience and Nanotechnology, 2014, 14(1): 332-343.
DOI:10.1166/jnn.2014.9141

摘要

The interest of researchers in utilizing nanomaterials as carriers for a wide spectrum of molecules has exploded in the last two decades. Nanodiamonds are one class of carbon-based nanomaterials that have emerged as promising drug delivery vehicles and imaging probes. Their ease of functionalization also led to the generation of stimuli-responsive nanodiamonds that deliver drugs on demand in a controlled manner. The ample surface area of NDs allowed for a higher loading of not only small molecules but also macromolecules like genes and proteins. Recently, the unique surface of NDs has attracted more attention as catalyst support in a huge range of organic modification and C-C bond formation reactions. Herein, recent advances in the utilization of nanodiamonds as a drug delivery vehicle and catalytical support are highlighted and summarized to illustrate the potential and versatility of this cheap and commercially available nanomaterial.

  • 出版日期2014-1