A novel two-step kit for topical treatment of tinea pedis - an open study

作者：Shemer A; Grunwald M H; Davidovici B; Nathansohn N; Amichai B^*

来源：Journal of the European Academy of Dermatology and Venereology, 2010, 24(9): 1099-1101.

DOI：10.1111/j.1468-3083.2010.03576.x

• tinea pedis
• topical treatment

Background
Tinea pedis is a common skin disease affecting most of the population during their lifetime. Topical and systemic treatments give only temporary relief.
Objective
To evaluate the efficacy and safety of a new topical treatment for moderate-to-severe tinea pedis.
Methods
Fifty patients suffering from tinea pedis were treated in two stages: the active stage - single use of the novel topical solution for 45 min and novel cream twice weekly for 4 weeks; the preventive stage - cream application once weekly for 10 months.
Results
Forty-five patients completed the active stage and achieved 76% cure rate. The medication was well tolerated; one patient dropped from the study because of very mild irritation. No other topical or systemic side effects were noted. Another five patients were lost to follow-up during the preventive stage. The total cure rate after the preventive stage was 70%.
Conclusions
This novel treatment was found to be effective, well tolerated and safe in the treatment of moderate and severe tinea pedis during the active and the preventive stages.

• 出版日期2010-9