Development, History, and Future of Automated Cell Counters

作者：Green Ralph^*; Wachsmann Hogiu Sebastian

来源：Clinics in Laboratory Medicine, 2015, 35(1): 1-+.

DOI：10.1016/j.cll.2014.11.003

• Automated cell counter
• Hematology
• Blood
• Hemoglobin
• Electrical impedance counting
• Flow cytometry
• Point of Care
• Light scattering

Modern automated hematology instruments use either optical methods (light scatter), impedance-based methods based on the Coulter principle (changes in electrical current induced by blood cells flowing through an electrically charged opening), or a combination of both optical and impedance-based methods. Progressive improvement in these instruments has allowed the enumeration and evaluation of blood cells with great accuracy, precision, and speed at very low cost. Future directions of hematology instrumentation include the addition of new parameters and the development of point-of-care instrumentation. In the future, in-vivo analysis of blood cells may allow noninvasive and near-continuous measurements.

• 出版日期2015-3