A novel surface-enhanced Raman spectroscopy substrate based on hybrid structure of monolayer graphene and Cu nanoparticles for adenosine detection

作者：Qiu, H. W.; Xu, S. C.; Chen, P. X.; Gao, S. S.; Li, Z.; Zhang, C.; Jiang, S. Z.^*; Liu, M.; Li, H. S.; Feng, D. J.

来源：Applied Surface Science, 2015, 332: 614-619.

DOI：10.1016/j.apsusc.2015.01.231

• Graphene
• Cu nanoparticles
• SERS
• Adenosine detection

We present a novel surface-enhanced Raman spectroscopy (SERS) substrate based on a double-deck hybrid system assembled by monolayer graphene and Cu nanoparticle layer. The monolayer graphene film was grown by chemical vapor deposition (CVD) technology. The Cu nanoparticles with a uniform distribution were synthesized by liquor-phase reduction synthesis (LPRS) method on the SiO2 (3 cm x 3 cm) substrate. By transferring graphene onto the Cu nanoparticle layer, we fabricated graphene/Cu nanoparticle hybrids (G/CuNPs) SERS substrate. The hybrid SERS substrate showed excellent Raman enhancement effect for adenosine. A reasonable linear response between the SERS intensity and adenosine concentration was obtained in the concentrations of 10(-2)-10(-6) M. This work provided amazing potential for sensitive label-free detection of biomolecular.

• 出版日期2015-3-30
• 单位德州学院; 山东大学; 山东师范大学