Amyloidosis and end-stage renal disease associated with leprosy

作者：da Silva Junior Geraldo Bezerra; Barbosa Orivaldo Alves; Barros Roseanne de Moura; Carvalho Priscila dos Reis; de Mendoza Talita Rodrigues; Sousa Barreto Dulce Maria; Barboza Celio Araujo; Carvalho Guimaraes Antonio Augusto; Daher Elizabeth de Francesco^*

来源：Revista da Sociedade Brasileira de Medicina Tropical, 2010, 43(4): 474-476.

• Leprosy
• End-stage renal disease
• Amyloidosis

Renal involvement in leprosy includes glomerulonephritis, amyloidosis and tubulointerstitial nephritis. A 58-year-old man was admitted with complaints of lower limb edema and dyspnea. At admission, nitrogen retention, anemia, hyperkalemia and metabolic acidosis were observed, requiring hemodialysis. The patient had a history of lepromatous leprosy. A renal biopsy was performed that was compatible with amyloidosis. The patient had a stable outcome, but without renal function recovery and remained on regular hemodialysis. Leprosy should be investigated in every patient with renal function loss, particularly in those with cutaneous lesions or other manifestations suggestive of leprosy.

• 出版日期2010-8