Bisphosphonate Therapy and Atypical Fractures

作者：Saleh Anas; Hegde Vishal V; Potty Anish G; Lane Joseph M^*

来源：Orthopedic Clinics of North America, 2013, 44(2): 137-+.

DOI：10.1016/j.ocl.2013.01.001

• Bisphosphonate therapy
• Atypical fractures
• Osteoporosis
• Atypical femoral fractures

Atypical femoral fractures have attracted a great deal of attention and controversy in the osteoporosis community because of their association with prolonged bisphosphonate therapy. The purpose of this article is to review the epidemiologic evidence linking bisphosphonates to atypical fractures and to highlight the potential pathologic mechanisms involved in such fractures. A management plan is provided based on the available evidence.

• 出版日期2013-4