A unique water soluble formulation of beta-asarone from sweet flag (Acorus calamus L.) and its in vitro activity against some fungal plant pathogens

作者：Shenvi Suvarna; Vinod; Hegde Rajendra; Kush Anil; Reddy G Chandrasekara^*

来源：Journal of Medicinal Plants Research, 2011, 5(20): 5132-5137.

• Acorus calamus L.
• beta-asarone
• beta methyl cyclodextrin (BMCD)
• Phytophthora
• internal transcribed spacer polymerase chain reaction (ITS PCR)
• zoospore

An antifungal substance beta-asarone was isolated from ethyl acetate extract of Acorus calamus L. As beta-asarone is lipophilic, it was made into water soluble formulation by encapsulating into beta methyl cyclodextrin (BMCD). At beta-asarone concentration of 30 ppm, this formulation completely inhibited mycelial growth of major plant pathogenic fungi, Phytophthora capsici, which was isolated from infected black pepper (Piper nigrum L.) leaf and identified by internal transcribed spacer polymerase chain reaction (ITS PCR) and sequencing. Further, this formulation completely inhibited the germination of zoospore and complete cessation of zoospore motility was observed within a minute.

• 出版日期2011-9-30