Much Ado about Zero

作者:Boeke Jef D*; Fenyo David
来源:Cell, 2015, 163(3): 534-535.
DOI:10.1016/j.cell.2015.10.033

摘要

LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.

  • 出版日期2015-10-22

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