A dynamic network perspective of chronic pain

作者：Farmer Melissa A; Baliki Marwan N; Apkarian A Vania^*

来源：Neuroscience Letters, 2012, 520(2): 197-203.

DOI：10.1016/j.neulet.2012.05.001

• Chronic pain
• Functional magnetic resonance imaging
• Network
• Diffusion tensor imaging
• Neuroplasticity
• Learning

We briefly summarize recent advances regarding brain functional representation of chronic pain, reorganization of resting state brain activity, and of brain anatomy with chronic pain. Based on these observations and recent theoretical advances regarding network architecture properties, we develop a general concept of the dynamic interplay between anatomy and function as the brain progresses into persistent pain, and outline the role of mesolimbic learning mechanisms that are likely involved in maintenance of chronic pain.

• 出版日期2012-6-29
• 单位西北大学