An efficient route to 1,8-dioxo-octahydroxanthenes and -decahydroacridines using a sulfated zirconia catalyst

作者：Kahandal Sandeep S; Burange Anand S^*; Kale Sandip R; Prinsen Pepijn; Luque Rafael; Jayaram Radha V^*

来源：Catalysis Communications, 2017, 97: 138-145.

DOI：10.1016/j.catcom.2017.03.017

• 1,8-dioxo-octahydroxanthenes
• 1,8-dioxo-decahydroacridines
• Sulfated zirconia
• Heterogeneous catalyst

Sulfated zirconia results to be a very efficient catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes and 1,8-dioxo-decahydroacridines without tedious work-up procedures. While 1,8-dioxo-octahydroxanthenes are prepared from aldehyde and 5,5-dimethyl-1,3-cyclohexenedione (dimedone), 1,8-dioxo-decahydroacridines are prepared from this reactant mixture with amines. This method provides a mild catalytic protocol for the synthesis of functionalized xanthene and acridine derivatives. The catalysts were characterized by XRD, FT-IR, TGA-DSC, SEM-EDAX and surface acidity and showed excellent re-usability up to 6 consecutive cycles.

• 出版日期2017-7-5