A Suzuki coupling approach to trifluoromethyl derivative of Targretin (LGD 1069)

作者:Qing FL*; Fan JF
来源:Bioorganic & Medicinal Chemistry Letters, 1997, 7(16): 2117-2120.
DOI:10.1016/S0960-894X(97)00382-X

摘要

The palladium-catalyzed Suzuki coupling reaction o-trifluoromethylated arylboronic acid (4) under bar and vinyl triflate (5) under bar provided the trifluoromethyl derivative of Targretin (LGD1069).