DIVERGENT SYNTHESIS OF 2,3,5-SUBSTITUTED THIOPHENES BY C-H ACTIVATION/BORYLATION/SUZUKI COUPLING

作者：Kallepalli Venkata A; Sanchez Luis; Li Hao; Gesmundo Nathan J; Turton Clarissa L; Maleczka Robert E Jr^*; Smith Milton R III

来源：Heterocycles, 2010, 80(2): 1429-1448.

DOI：10.3987/COM-09-S(S)135

• Thiophene
• C-H Activation
• Boronic Ester
• Suzuki Coupling Reaction
• COX-2

C-H activation/borylation has been married with Suzuki coupling to prepare DuP 697 (1) and analogs that would be otherwise difficult to obtain via the traditional synthetic route to 1.

• 出版日期2010-3-1