A ratiometric fluorescent hydrogen peroxide chemosensor manipulated by an ICT- activated FRET mechanism and its bioimaging application in living cells and zebrafish

作者：Xu, Kaixin; He, Longwei; Yang, Xueling; Yang, Yunzhen; Lin, Weiying^*

来源：Analyst, 2018, 143(15): 3555-3559.

DOI：10.1039/c8an00842f

• IN-VIVO
• OXIDATIVE STRESS
• SELECTIVE DETECTION
• RATIONAL DESIGN
• REACTIVE OXYGEN
• LIVE TISSUE
• PROBE
• MITOCHONDRIA
• EMISSION
• H2O2

A H2O2-responsive fluorescent chemosensor (CNBE) with a ratiometric emission signal was elaborately designed and synthesized. The ratio signal of the chemosensor was manipulated by an interplaying ICT-activated FRET mechanism. The ratiometric fluorescence imaging was successfully applied to detect H2O2 using CNBE in living cells and zebrafish.

• 出版日期2018-8-7
• 单位济南大学