Multimeric, Multifunctional Derivatives of Poly(ethylene glycol)

作者：Zacchigna Marina^*; Cateni Francesca; Drioli Sara; Bonora Gian Maria

来源：Polymers, 2011, 3(3): 1076-1090.

DOI：10.3390/polym3031076

• poly(ethylene glycol)
• multifunctional polymers
• conjugation
• drug delivery

This article reviews the use of multifunctional polymers founded on high-molecular weight poly(ethylene glycol) (PEG). The design of new PEG derivatives assembled in a dendrimer-like multimeric fashion or bearing different functionalities on the same molecule is described. Their use as new drug delivery systems based on the conjugation of multiple copies or diversely active drugs on the same biocompatible support is illustrated.

• 出版日期2011-9