ANTIOXIDANT AND ACETYLCHOLINESTERASE ACTIVITIES OF THREE SPECIES OF THE FAMILY LAMIACEAE

作者：Sadashiva C T^*; Naidoo Y; Naidoo J R; Kalicharan B; Naidoo G

来源：Bangladesh Journal of Botany, 2014, 43(3): 331-335.

• Lamiaceae
• Antioxidant activity
• Acetylcholinesterase inhibition

Antioxidant and acetylcholinesterase inhibitory activity of the three species namely, Endostemon obtusifolius (E. Mey. ex benth.) N. E. Br, Plectranthus zuluensis (T. Cooke) and Tetradenia riparia (Hochst.) Codd. were evaluated. Maximum antioxidant activity was exhibited by E. obtusifolius (IC50 130 mu g/ml) followed by T. riparia (IC50 142 mu g/ml) and P. zuluensis (IC50 169 mu g/ml). Acetylcholinesterase inhibition (AChEI) was highest in P. zuluensis (IC50 290 mu g/ml) followed by E. obtusifolius (IC50 470 mu g/ml) and T. riparia (IC50 750 mu g/ml). The results suggest that these three species possess natural antioxidants and acetylcholinesterase inhibitors, which may be beneficial for the treatment of Alzheimer%26apos;s disease, that require high concentration of these compounds.

• 出版日期2014-12