Short-term Outcomes After Esophagectomy at 164 American College of Surgeons National Surgical Quality Improvement Program Hospitals Effect of Operative Approach and Hospital-Level Variation

作者：Merkow Ryan P^*; Bilimoria Karl Y; McCarter Martin D; Phillips Joseph D; DeCamp Malcolm M; Sherman Karen L; Ko Clifford Y; Bentrem David J

来源：Archives of Surgery, 2012, 147(11): 1009-1016.

Hypothesis: When assessing the effect of operative approach on outcomes, it may be less relevant whether a transhiatal or an Ivor Lewis esophagectomy was performed and may be more important to focus on patient selection and the quality of the hospital performing the operation.
Design: Observational study.
Setting: Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program.
Patients: Individuals undergoing esophagectomy were identified from January 1, 2005, to December 31, 2010. The following 4 groups were created based on operative approach: transhiatal, Ivor Lewis, 3-field, and any approach with an intestinal conduit.
Main Outcome Measures: Risk-adjusted 30-day outcomes and hospital-level variation in performance.
Results: At 164 hospitals, 1738 patients underwent an esophageal resection: 710 (40.9%) were transhiatal, 497 (28.6%) were Ivor Lewis, 361 (20.8%) were 3-field, and 170 (9.8%) were intestinal conduits. Compared with the transhiatal approach, Ivor Lewis esophagectomy was not associated with increased risk for postoperative complications; however, 3-field esophagectomy was associated with increased likelihood of postoperative pneumonia (odds ratio [OR], 1.88; 95% CI, 1.28-2.77) and prolonged ventilation exceeding 48 hours (OR, 1.68; 95% CI, 1.16-2.42). Intestinal conduit use was associated with increased 30-day mortality (OR, 2.65; 95% CI, 1.08-6.47), prolonged ventilation exceeding 48 hours (OR, 1.61; 95% CI, 1.01-2.54), and return to the operating room for any indication (OR, 1.85; 95% CI, 1.16-2.96). Patient characteristics were the strongest predictive factors for 30-day mortality and serious morbidity. After case-mix adjustment, hospital performance varied by 161% for 30-day mortality and by 84% for serious morbidity.
Conclusions: Compared with transhiatal dissection, Ivor Lewis esophagectomy did not result in worse postoperative complications. After controlling for case-mix, hospital performance varied widely for all outcomes assessed, indicating that reductions in short-term outcomes will likely result from expanding other aspects of hospital quality beyond a focus on specific technical maneuvers. Arch Surg. 2012;147(11):1009-1016

• 出版日期2012-11
• 单位西北大学