Detection of NDM-1-Producing Klebsiella pneumoniae in Kenya

作者：Poirel Laurent; Revathi Gunturu; Bernabeu Sandrine; Nordmann Patrice^*

来源：Antimicrobial Agents and Chemotherapy, 2011, 55(2): 934-936.

DOI：10.1128/AAC.01247-10

Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla(NDM-1) carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including beta-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

• 出版日期2011-2