Comparison of nasogastric feeding versus nasojejunal feeding for severe acute pancreatitis: a systematic review and meta-analysis

作者：Guo, Ying-Jie; Jing, Xue; Tian, Zi-Bin^*

来源：International Journal of Clinical and Experimental Medicine, 2016, 9(11): 22814-22823.

• Severe acute pancreatitis
• nasogastric
• nasojejunal
• enteral nutrition
• meta-analysis

Nasogastric (NG) and Nasojejunal (NJ) feeding are feasible ways in enteral nutrition (EN) of severe acute pancreatitis (SAP). However, which is the optimal approach has long been debated among experts. This meta-analysis was to examine the differences in efficacy and safety of the two routes for patients with SAP. We searched the Cochrane Library, PubMed, EM base Databases, Web of Science, Wanfang Data base, China National Knowledge Infrastructure (CNKI), China Biology Medicine disc (CBM disc). Prospective clinical controlled trials comparing NG and NJ feeding in patients with SAP were eligible for inclusion. Total of 446 patients with SAP from nine clinical controlled trials were identified and included in our study, involving 229 patients in NGEN group and 217 in NJEN group. There were no significant differences between the two groups in the risk of mortality, infectious complications, exacerbation of pain, diarrhoea, tube displacement, conversion to surgery, intolerance of feeding, achievement of energy balance. Nasogastric feeding was considered effective and well tolerated when compared with nasojejunal feeding through this meta, and the former is more economical and convenient. NG feeding, which eases the administration of enteral nutrients in the clinical setting, may be the preferred way in patients with SAP.

• 出版日期2016
• 单位青岛大学