An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

作者：Fang Chiew San; Oh Kyung Hwan; Oh Aram; Lee Kwangyeol; Park Seonhwa; Kim Sinyoung; Park Jin Kyoon; Yang Haesik^*

来源：Chemical communications, 2016, 52(34): 5884-5887.

DOI：10.1039/c6cc00353b

This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR-and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.

• 出版日期2016