科研之友
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摘要
The direct C-3 alkylation of indoles with primary and secondary alcohols through the combination of KOH and an N-heterocyclic carbene is described. The KOH/NHC-catalysed system can give desired C-3 alkylated indoles with high selectivity in moderate to excellent yields. Moreover, this process has obvious advantages such as high atom economy and the absence of a metal source.
- 出版日期2015-8
- 单位南京理工大学
