Au-catalyzed domino process synthesis of imidazo[1,2-a]pyridines from 2-aminopyridine and N-tosylhydrazones: An efficient C-N bond formation reaction

作者：Guo, Pengfeng; Huang, Shuyu; Mo, Jiaxian; Chen, Xiaoyan; Jiang, Hangqi; Chen, Weifeng; Cai, Hehuan; Zhan, Haiying^*

来源：Catalysis Communications, 2017, 90: 43-46.

DOI：10.1016/j.catcom.2016.10.033

• Au-catalyzed
• Imidazo[1,2-a]pyridines
• Synthesis
• Molecular oxygen

A novel Au-catalyzed domino reaction for the synthesis of imidazo[1,2-a]pyridines from 2-aminopyridine and N-tosylhydrazones has been developed using molecular oxygen. It represents a new strategy for the formation of C-N bonds. This transformation demonstrated a broad tolerance toward the substrates and allowed the generation of a diverse imidazo[1,2-a]pyridine derivatives with good yields.

• 出版日期2017-2
• 单位广东药科大学