Application of N-thiocyanatosuccinimide as a reagent for the facile conversion of epoxides into thiocyanohydrines

作者：Mokhtari Babak^*; Azadi Roya; Rahmani Nezhad Samira

来源：Chinese Chemical Letters, 2011, 22(1): 21-24.

DOI：10.1016/j.cclet.2010.09.004

• N-Thiocyanatosuccinimide
• Ring opening
• Epoxide
• Thiocyanohydrin

The use of in situ generated N-thiocyanatosuccinimide with NH4SCN offers an efficient reagent system for the conversion of epoxides into their corresponding thiocyanohydrines in good to high yields. The major advantages of this method are as follows: use of cheap reagent, high regioselectivity, simple availability of reagent, ease of workup of the reaction.

• 出版日期2011-1