Amorphous calcium phosphates synthesized by precipitation from calcium D-gluconate solutions

作者：Medvecky L^*; Sopcak T; Girman V; Briancin J

来源：Colloids and Surfaces A: Physicochemical and Engineering Aspects , 2013, 417: 191-200.

DOI：10.1016/j.colsurfa.2012.11.015

• Calcium D-gluconate
• Hydroxyapatite
• TEM
• Phase analysis
• FTIR spectroscopy
• Tricalcium phosphate

The amorphous calcium phosphates were synthesized by the precipitation from non-toxic calcium D-gluconate precursor solutions. The low number of nanosized well-ordered calcium deficient hydroxyapatite clusters separated with amorphous calcium phosphate matrix was found at short aging times. The content of intramolecular water in aggregates decreased with an amount of well-ordered clusters and maturation time. The majority alpha-tricalcium phosphate phase and calcium deficient calcium phosphate were formed after annealing of samples with a high volume fraction of amorphous matrix and nanocrystalline apatite-like phase respectively. The very fine nanocrystalline calcium deficient hydroxyapatite was intermediate phase during thermal transformation to the final beta-tricalcium phosphate. The rise of disaggregation of coarse particles to smaller well-ordered hydroxyapatite clusters with aging time was verified. The different amount and size of nanocrystalline clusters were responsible for the formation of various calcium phosphate phases after thermal treatment.

• 出版日期2013-1-20