Axially chiral dicarboxylic acid-catalyzed asymmetric imino aza-enamine reaction/oxidation as a Strecker reaction surrogate

作者:Hashimoto Takuya; Kimura Hidenori; Maruoka Keiji*
来源:Tetrahedron: Asymmetry , 2010, 21(9-10): 1187-1188.
DOI:10.1016/j.tetasy.2010.04.067

摘要

Axially chiral dicarboxylic acid-catalyzed highly enantioselective imino aza-enamine reaction was elaborated into a surrogate of the asymmetric Strecker reaction building on the fact that the N,N-dialkylhydrazone moiety can be easily converted to the cyanide moiety by treatment with peracid.

  • 出版日期2010-5-17