Novel picornavirus in domesticated common quail (Coturnix coturnix) in Hungary

作者：Pankovics Peter; Boros Akos; Reuter Gabor^*

来源：Archives of Virology, 2012, 157(3): 525-530.

DOI：10.1007/s00705-011-1192-8

This study reports the detection of a novel picornavirus in domesticated common quail (Coturnix coturnix) in Hungary. The 8159-nucleotide (nt)-long RNA genome of this virus, named quail picornavirus (QPV1-HUN/2010; JN674502), shows only 43%, 39% and 47% amino acid (aa) identity in the P1 (857 aa), P2 (458 aa) and P3 (777 aa) coding regions respectively, to the closest reference, avian sapelovirus. The 5'UTR contains a variant type IV IRES with a 20-nt-long apical "8"-like structure that is conserved in avian-origin and seal picornaviruses. The 390-aa-long L protein is cysteine rich and encodes two copies of a 34-aa-long repeat motif. Quail picornavirus represents a novel picornavirus species and perhaps a novel genus.

• 出版日期2012-3