Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results

作者：De Felice Francesca; Musio Daniela; Gravina Giovanni Luca; Marampon Francesco; Tombolini Vincenzo

来源：Oncotarget, 2016, 7(48): 80077-80082.

DOI：10.18632/oncotarget.11374

• radiotherapy
• stage I seminoma
• surveillance
• chemotherapy
• orchiectomy

Aim: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma.
Method: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy.
Results: A total of 85 patients were included. The median follow-3up was 15 years. The 20-3year overall survival (OS) and relapse free survival (RFS) were 92% and 96.3%, respectively. No severe acute and late complications were recorded. Overall 5.9% of patients had a second unrelated malignancy.
Conclusion: Adjuvant RT is an efficacious and safe treatment in stage I seminoma.

• 出版日期2016-11-29