Phosphoinositide phosphatases and disease

作者：Majerus Philip W^*; York John D

来源：The Journal of Lipid Research, 2009, 50: S249-S254.

DOI：10.1194/jlr.R800072-JLR200

• membrane trafficking
• lipid code
• kinase
• myotubularin
• Lowe syndrome
• Charcot-Marie-Tooth disease
• Jobert syndrome

The field of inositol signaling has expanded greatly in recent years. jlr Given the many reviews on phosphoinositide kinases, we have chosen to restrict our discussion to inositol lipid hydrolysis focused on the phosphatases and a brief mention of the lipase isoforms. We also discuss recent discoveries that link mutations in phosphoinositide phosphatases to disease.-Majerus, P. W., and J. D. York. Phosphoinositide phosphatases and disease. J. Lipid Res. 2009. S249-S254.

• 出版日期2009-4