A conventional approach to the total synthesis of (-)-varitriol

作者:Vamshikrishna K; Srihari P*
来源:Tetrahedron: Asymmetry , 2012, 23(22-23): 1584-1587.
DOI:10.1016/j.tetasy.2012.10.010

摘要

The stereoselective total synthesis of (-)-varitriol has been achieved starting from commercially available D-(-)-ribose and o-anisic acid. A Mitsunobu reaction, Julia-Kocienski olefination, and one pot reduction of both ester and iodo functionalities with superhydride are the key reactions involved in this synthesis.

  • 出版日期2012-12-15