Altered Eosinophil Proteome in a Patient with Hypereosinophilia from Acute Fascioliasis

作者:Straub Christof; Burnham Jason P; White A Clinton Jr*; Pazdrak Konrad; Sanchez Cesar; Carlos Watanabe Luis; Kurosky Alexander; Montes Martin
来源:Clinical and Vaccine Immunology, 2011, 18(11): 1999-2002.
DOI:10.1128/CVI.05373-11

摘要

We used comparative proteomics to analyze eosinophils from a patient with hypereosinophilia due to fascioliasis. Using 2-dimensional electrophoresis and mass spectrometry, we demonstrated that the eosinophil proteome was significantly altered compared to those of healthy controls.