An umpolung approach toward N-aryl nitrone construction: a phosphine-mediated addition of 1,2-dicarbonyls to nitroso electrophiles

作者:Chavannavar Aditi P; Oliver Allen G; Ashfeld Brandon L*
来源:Chemical Communications, 2014, 50(74): 10853-10856.
DOI:10.1039/c4cc05044d

摘要

An umpolung approach toward nitrone construction utilizing a phosphine-mediated addition of 1,2-dicarbonyls to nitroso compounds is reported. The reaction exhibits a high degree of chemoselectivity and provides direct access to isoxazolidines, imines, and trisubstituted alkenes.

  • 出版日期2014

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