Antibiotics for Gram-Positive Bacterial Infections: Vancomycin, Teicoplanin, Quinupristin/Dalfopristin, Oxazolidinones, Daptomycin, Dalbavancin, and Telavancin

作者：Nailor Michael D; Sobel Jack D^*

来源：Infectious Disease Clinics of North America, 2009, 23(4): 965-+.

DOI：10.1016/j.idc.2009.06.010

• Gram positive bacteria
• Vancomycin
• Daptomycin
• Linezolid
• Quinupristin
• Dalfopristin
• MRSA
• VRE

An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. The emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control this emergence of resistance are expected to be proposed. Newer antimicrobial agents that have activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.

• 出版日期2009-12