A single genotype of Acinetobacter baumannii expresses multiple antibiotic susceptibility phenotypes

作者:Wiemken Timothy L*; Curran Daniel; Kelley Robert R; Khan Mohammad S S; Carrico Ruth M; Pacholski Emily B; Ramirez Julio A
来源:American Journal of Infection Control, 2014, 42(5): 556-558.
DOI:10.1016/j.ajic.2014.01.003

摘要

It is common practice to define a bacterium with unequal antibiotic susceptibility phenotypes as a different genotype. Here, we describe the utility of this practice for Acinetobacter baumannii. We determined antibiotic susceptibility for 19 clinical isolates of A baumannii. Repetitive sequence polymerase chain reaction method was used to determine genotypes. Although all isolates were of the same genotype, 79% were predicted to be different based on susceptibility patterns. The antibiotic susceptibility phenotype does not accurately predict the genotype of A baumannii.

  • 出版日期2014-5