An indirect electric field-induced control in directional migration of rat mesenchymal stem cells

作者：Park Hyoun Hyang; Jo Sungkwon; Seo Cheong Hoon; Jeong Je Hoon; Yoo Yeong Eun; Lee Dae Hoon^*

来源：Applied Physics Letters, 2014, 105(24): 244109.

DOI：10.1063/1.4904801

We present the efficacy of an indirect E-field on the directional migration of rat mesenchymal stem cell (MSC). To avoid current flow through culture media and cell, E-fields were generated without exposing electrodes directly to the cell media. MSC migration was observed during wound closure in presence of indirect E-field. MSC migration depended on the E-field strength and occurs predominantly in the anodal direction. Indirect E-field therapy proved as tentative tool for controlled cell movement and healing.

• 出版日期2014-12-15