Aqueous C-S cross-coupling: synthesis of 2-iminobenzo-1,3-oxathioles via CuCl2 center dot H2O-catalyzed tandem reaction of 2-iodophenols with isothiocyanates

作者：Ding, Qiuping^*; Liu, Xianjin; Cao, Banpeng; Zong, Zhenzhen; Peng, Yiyuan

来源：Tetrahedron Letters, 2011, 52(16): 1964-1967.

DOI：10.1016/j.tetlet.2011.02.061

• Isothiocyanate
• 2-Iodophenol
• Cross-coupling
• Aqueous

A CuCl2 center dot H2O-catalyzed tandem reaction of 2-iodophenol with isothiocyanate in water is described, which provides an environmentally benign, efficient, and practical route for the generation of 2-iminobenzo-1,3-oxathiole. It was noteworthy that most of the products were easily separated from the reaction system by simple filtration.

• 出版日期2011-4-20
• 单位江西师范大学