Age-Related Changes in Anterior, Posterior, and Total Corneal Astigmatism

作者：Ueno Yuta^*; Hiraoka Takahiro; Beheregaray Simone; Miyazaki Maki; Ito Mutsuko; Oshika Tetsuro

来源：Journal of Refractive Surgery, 2014, 30(3): 192-197.

DOI：10.3928/1081597X-20140218-01

PURPOSE: To evaluate age-related changes in anterior, posterior, and total corneal astigmatism by comparing simulated keratometric astigmatism to total corneal astigmatism.
METHODS: Corneal topography of the anterior and posterior surfaces was evaluated using three-dimensional optical coherence tomography in 419 patients with normal eyes (218 men and 201 women) with ages ranging from 8 to 93 years (mean +/- standard deviation: 49.5 +/- 23.1 years). Keratometric astigmatism was calculated using the keratometric index (1.3375) and radius of the anterior corneal curvature; anterior and posterior corneal curvature measurements were used to calculate total corneal astigmatism.
RESULTS: The keratometric and total astigmatism were 1.08 +/- 0.71 diopters (D) and 1.03 +/- 0.69 D, respectively. Vector analysis revealed a mean difference between keratometric and total astigmatism of 0.24 +/- 0.09 D, which showed a significant correlation to age (P < .0001). In eyes with with-the-rule astigmatism, keratometric astigmatism overestimated total astigmatism. In eyes with against-the-rule astigmatism, keratometric astigmatism underestimated total astigmatism.
CONCLUSIONS: The anterior corneal surface shifts from with-the-rule to against-the-rule astigmatism with aging, whereas the posterior corneal surface remains as against-the-rule astigmatism in most cases. The variation in the anterior astigmatism is the most important factor contributing to this change. Total corneal astigmatism is a better predictor than keratometric astigmatism for selecting toric intraocular lenses.

• 出版日期2014-3