Processing speed and working memory training in multiple sclerosis: A double-blind randomized controlled pilot study

作者：Hancock Laura M^*; Bruce Jared M; Bruce Amanda S; Lynch Sharon G

来源：Journal of Clinical and Experimental Neuropsychology, 2015, 37(2): 113-127.

DOI：10.1080/13803395.2014.989818

• Processing speed
• Multiple sclerosis
• Computer-based training
• Cognitive training
• Working memory

Between 40-65% of multiple sclerosis patients experience cognitive deficits, with processing speed and working memory most commonly affected. This pilot study investigated the effect of computerized cognitive training focused on improving processing speed and working memory. Participants were randomized into either an active or a sham training group and engaged in six weeks of training. The active training group improved on a measure of processing speed and attention following cognitive training, and data trended toward significance on measures of other domains. Results provide preliminary evidence that cognitive training with multiple sclerosis patients may produce moderate improvement in select areas of cognitive functioning.

• 出版日期2015-2-7