An in Situ Generated Palladium on Aluminum Oxide: Applications in Gram-Scale Matsuda-Heck Reactions

作者:Pape Simon; Dauksaite Lauryna; Lucks Sandra; Gu Xiaoting; Brunner Heiko
来源:Organic Letters, 2016, 18(24): 6376-6379.
DOI:10.1021/acs.orglett.6b03268

摘要

In situ generated palladium on aluminum oxide provides an active catalytic system for Matsuda-Heck reactions in gram-scale. The novel catalyst proceeded through a significantly higher catalytic activity compared to the classical Pd/C system. Based on the high catalytic activity the first alpha,beta,beta-triarylation of methyl acrylate in good yields could be provided in one-step.

  • 出版日期2016-12-16