Atypical fibroxanthoma management: Recurrence, metastasis and disease-specific death

作者：Polcz Margit Marisa^*; Sebaratnam Deshan Frank; Fernandez Penas Pablo

来源：Australasian Journal of Dermatology, 2018, 59(1): 10-25.

DOI：10.1111/ajd.12646

• AFX
• AFX management
• AFX treatment
• atypical fibroxanthoma
• review

Atypical fibroxanthoma (AFX) is a rare spindle cell neoplasm predominantly found on the head and neck of elderly individuals with sun-damaged skin, with no evidence-based guidelines for their management. A systematic retrospective review of the literature focusing on treatment modality found a recurrence and metastasis rate of 8.0% (5.6% when adjusted for incomplete excisions) and 0.5% for local excision and 4.6% and 3.2% for Mohs micrographic surgery, respectively. Our results suggest that with clear surgical margins, AFX is unlikely to recur and metastases are rare, with significantly higher rates in the immunosuppressed population.

• 出版日期2018-2