A pilot study on total, corneal, and internal aberrations in insulin-dependent and non-insulin-dependent diabetes mellitus patients

作者：Calvo Maroto Ana M; Perez Cambrodi Rafael J; Garcia Lazaro Santiago; Albarran Diego Cesar; Cervino Alejandro^*

来源：Graefes Archive for Clinical and Experimental Ophthalmology, 2015, 253(4): 645-653.

DOI：10.1007/s00417-014-2864-3

• Diabetes mellitus
• Ocular optical quality
• Wavefront aberrations

To explore the distribution of total, corneal, and internal higher-order aberrations (HOAs) in both insulin-dependent (IDDM) and non-insulin-dependent (NIDDM) diabetic patients.
Pilot study including seven patients with IDDM (14 eyes) and 11 patients with NIDDM (22 eyes). Ocular HOAs were examined using ray tracing aberrometry (i-Trace, Tracey Technologies Corp., Houston, TX) and the measurements of anterior segment using Scheimpflug imaging (Pentacam, Oculus Inc. Germany).
Total HOAs was slightly higher in IDDM (0.634 +/- 0.228 mu m, 95% IC +/- 0.131) than in NIDDM patients (0.527 +/- 0.245 mu m, 95% IC +/- 0.108) (p = 0.267). The greatest contributor for total ocular HOAs was internal vertical coma (Z(3) (-aEuro parts per thousand 1)) for both diabetic groups. In NIDDM, age and central corneal thickness (CCT) were correlated with total HOAs (p < 0.001, p = 0.0180 respectively); however, anterior chamber volume (ACV) was inversely correlated with total HOAs (p = 0.019). In IDDM, total HOAs were correlated with posterior asphericity (Q) (p = 0.002) and inversely correlated with ageing (p = 0.013).
Diabetic patients showed high values of total and internal vertical coma (Z(3) (-aEuro parts per thousand 1)). There might be a role for optical quality measurements in monitoring changes due to DM.

• 出版日期2015-4