科研之友
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摘要
Menetrier disease is a rare hypertrophic gastropathy that is characterized by hyperplasia of the mucous cells with concurrent loss of chief and parietal cells within the gastric glands. There are few reports of this disease in dogs, and little is known about the clinical presentation and progression of canine Menetrier disease. Three Cairn terrier littermates developed hypertrophic gastropathy with histological features of Menetrier disease. One dog remained clinically asymptomatic for 2 years after diagnosis. The development of this disease in 3 siblings suggests a possible inherited predisposition. All 3 dogs also developed gastric neoplasia, which has been reported in human Menetrier disease but has not been associated previously with hypertrophic gastropathy in domestic species.
- 出版日期2012-11
