Design, Synthesis, and Biological Evaluations of Several Y-26732 Analogues

作者：Wang Xinran; Chen Ligong^*; Li Hang; Sun Changhai; Qi Haofei; Wang Donghua

来源：Journal of Heterocyclic Chemistry, 2015, 52(4): 1212-1218.

DOI：10.1002/jhet.2238

A series of pyridine Rho kinase inhibitors were designed and synthesized utilizing the ligand-binding pocket model with Y-26732 as the lead compound. These compounds were evaluated on cell lines for their biological activities.

• 出版日期2015-7
• 单位天津大学