A methodology for in silico endovascular repair of abdominal aortic aneurysms

作者：Hemmler Andre; Lutz Brigitta; Reeps Christian; Kalender Gunay; Gee Michael W^*

来源：Biomechanics and Modeling in Mechanobiology, 2018, 17(4): 1139-1164.

DOI：10.1007/s10237-018-1020-0

• Abdominal aortic aneurysm
• Endovascular aneurysm repair
• Stent-graft
• Oversizing
• Finite element method

Endovascular aneurysm repair (EVAR) can involve some unfavorable complications such as endoleaks or stent-graft (SG) migration. Such complications, resulting from the complex mechanical interaction of vascular tissue, SG and blood flow or incompatibility of SG design and vessel geometry, are difficult to predict. Computational vascular mechanics models can be a predictive tool for the selection, sizing and placement process of SGs depending on the patient-specific vessel geometry and hence reduce the risk of potential complications after EVAR. In this contribution, we present a new in silico EVAR methodology to predict the final state of the deployed SG after intervention and evaluate the mechanical state of vessel and SG, such as contact forces and wall stresses. A novel method to account for residual strains and stresses in SGs, resulting from the precompression of stents during the assembly process of SGs, is presented. We suggest a parameter continuation approach to model various different sizes of SGs within one in silico EVAR simulation which can be a valuable tool when investigating the issue of SG oversizing. The applicability and robustness of the proposed methods are demonstrated on the example of a synthetic abdominal aortic aneurysm geometry.

• 出版日期2018-8