A Ring Expansion-Glycosylation Strategy toward the Synthesis of Septano-oligosaccharides

作者:Sridhar Perali Ramu*; Venukumar Patteti
来源:Organic Letters, 2012, 14(21): 5558-5561.
DOI:10.1021/ol302677z

摘要

A one-pot ring-expansion-glycosylation reaction was performed using 1,2-cyclopropanated sugars as glycosyl donors and carbohydrate O-nucleophiles as acceptors to provide septanohexose mimics of pyranose and furanose derivatives. The methodology was successfully extended to the synthesis of septano-oligosaccharides by adopting a divergent strategy as well as an iterative protocol.

  • 出版日期2012-11-2