A program for ligation at threonine sites: application to the controlled total synthesis of glycopeptides

作者：Chen Jin; Wang Ping; Zhu Jianglong; Wan Qian; Danishefsky Samuel J^*

来源：Tetrahedron, 2010, 66(13): 2277-2283.

DOI：10.1016/j.tet.2010.01.067

A method by which to accomplish formal threonine ligation has been developed. The method accomplishes ligations of two peptide domains. We have also demonstrated the ability to successfully ligate two independent glycopeptide domains.

• 出版日期2010-3-27