New cycloartane triterpene glycosides from Beesia calthaefolia

作者：Li, Hong-Jie; Mu, Li-Hua; Dong, Xian-Zhe; Ge, Xiao-Yue; Liu, Ping^*

来源：Natural Product Research, 2013, 27(21): 1987-1993.

DOI：10.1080/14786419.2013.811407

• Beesia calthaefolia
• Ranunculaceae
• cycloartane triterpene glycosides
• inhibition
• splenocytes

Two new cycloartane triterpene glycosides (compounds 1 and 4) were isolated from the whole plants of Beesia calthaefolia with two known glycosides (compounds 2 and 3). Compounds 1 and 4 were assigned as (20S(*),24R(*))-16-acetoxy-20, 24-epoxy-9, 19-cyclolanostane-3,12,15,18,25-pentaol-3-O--d-xylopyranoside and (20S(*),24 R-*)-16-acetoxy-20,24-epoxy-9,19-cyclolanostane-3,15,18,25-tetraol-3-O--d-xylopyranoside, respectively. Their structures were elucidated on the basis of extensive spectroscopic data analyses and comparison with spectroscopic data reported. Compounds 1 and 4 showed potential inhibition activity for the proliferation of splenocytes.

• 出版日期2013-11-1
• 单位中国人民解放军总医院; 天津大学