A fermented barley and soybean formula enhances skin hydration

作者：Lee Sein; Kim Jong Eun; Suk Sujin; Kwon Oh Wook; Park Gaeun; Lim Tae gyu; Seo Sang Gwon; Kim Jong Rhan; Kim Dae Eung; Lee Miyeong; Chung Dae Kyun; Jeon Jong Eun; Cho Dong Woon; Hurh Byung Serk; Kim Sun Yeou; Lee Ki Won^*

来源：Journal of Clinical Biochemistry and Nutrition, 2015, 57(2): 156-163.

DOI：10.3164/jcbn.15-43

• skin hydration
• barley
• soybean
• ultraviolet B
• hyaluronan

Skin hydration is one of the primary aims of beauty and antiaging treatments. Barley (Hordeum vulgare) and soybean (Glycine max) are major food crops, but can also be used as ingredients for the maintenance of skin health. We developed a natural product-based skin treatment using a barley and soybean formula (BS) incorporating yeast fermentation, and evaluated its skin hydration effects as a dietary supplement in a clinical study. Participants ingested a placebo- (n =33) or BS- (3 g/day) containing drink (n = 32) for 8 weeks. A significant increase in hydration in the BS group as compared to the placebo group was observed on the faces of subjects after 4 and 8 weeks, and on the forearm after 4 weeks. Decreases in stratum corneum (SC) thickness were also observed on the face and forearm. BS enhanced hyaluronan (HA) and skin barrier function in vitro and reduced Hyal2 expression in human dermal fibroblasts (HDF). BS also recovered ultraviolet (UV) B-induced downregulation of HA in HaCaT cells. These results suggest that BS has promising potential for development as a health functional food to enhance skin health.

• 出版日期2015-9-1