A multicentric study regarding the use of hormone therapy during female mid-age (REDLINC VI)

作者：Bluemel J E; Chedraui P; Baron G; Benitez Z; Flores D; Espinoza M T; Gomez G; Gonzalez E; Hernandez L; Lima S; Martino M; Montano A; Monterrosa A; Mostajo D; Ojeda E; Onatra W; Robles C; Saavedra J; Sanchez H; Tserotas K; Vallejo M S; Vallejo C

来源：Climacteric, 2014, 17(4): 433-441.

DOI：10.3109/13697137.2014.882305

• HORMONE REPLACEMENT THERAPY
• USE
• PERCEPTIONS
• MENOPAUSE
• SYMPTOMS
• MENOPAUSE RATING SCALE

Background Menopausal hormone therapy (HT) has shown benefits for women; however, associated drawbacks (i.e. risks, costs, fears) have currently determined its low use. %26lt;br%26gt;Objective To determine the prevalence of current HT use among mid-aged women and describe the characteristics of those who have never used, have abandoned or are currently using HT. In addition, reasons for not using HT were analyzed. %26lt;br%26gt;Method This was a cross-sectional study that analyzed a total of 6731 otherwise healthy women (45-59 years old) of 15 cities in 11 Latin American countries. Participants were requested to fill out the Menopause Rating Scale (MRS) and a questionnaire containing sociodemographic data and items regarding the menopause and HT use. %26lt;br%26gt;Results The prevalence of current HT use was 12.5%. Oral HT (43.7%) was the most frequently used type of HT, followed by transdermal types (17.7%). The main factors related to the current use of HT included: positive perceptions regarding HT (odds ratio (OR) 11.53, 95% confidence interval (CI) 9.41-14.13), being postmenopausal (OR 3.47, 95% CI 2.75-4.36) and having a better socioeconomic level. A total of 48.8% of surveyed women had used HT in the past, but abandoned it due to symptom improvement or being unconcerned; fear of cancer or any other secondary effects were also reported but in less than 10%. Among women who had never used HT, 28% reported the lack of medical prescription as the main reason, followed by the absence of symptoms (27.8%). Among those reporting lack of prescription as the main reason for not using HT, 30.6% currently had severe menopausal symptoms (total MRS score %26gt;16); 19.5% of women were using alternative %26apos;natural%26apos; therapies, with 35.1% of them displaying severe menopausal symptoms as compared to a 22.5% observed among current HT users. %26lt;br%26gt;Conclusion The use of HT has not regained the rates observed a decade ago. Positive perceptions regarding HT were related to a higher use. Lack of medical prescription was the main reason for not using HT among non-users, many of whom were currently displaying severe menopausal symptoms.

• 出版日期2014-8