An elderly lady with significant weight loss

作者：Al Judaibi Bandar^*; Driman David K; Chandok Natasha

来源：Arab Journal of Gastroenterology, 2015, 16(1): 31-32.

DOI：10.1016/j.ajg.2014.10.003

• Collagenous sprue
• Coeliac disease
• Collagen band

We present a rare case of collagenous sprue in an elderly woman with significant weight loss and malnutrition. Collagenous sprue is a rare, female-predominant and immune-mediated gastrointestinal disease that can affect any part of the gut, and shares a strong association with Coeliac disease. The diagnosis is confirmed by gut histopathology demonstrating a subepithelial collagenous band and inflammatory infiltrate in the lamina propria. The pathogenesis and natural history is poorly elucidated, and treatment involves a gluten-free diet and/or immunomodulatory therapy.

• 出版日期2015-3