Antibacterial clerodane diterpenes from Goldenrod (Solidago virgaurea)

作者:Starks Courtney M*; Williams Russell B; Goering Matt G; O'; Neil Johnson Mark; Norman Vanessa L; Hu Jin Feng; Garo Eliane; Hough Grayson W; Rice Stephanie M; Eldridge Gary R
来源:Phytochemistry, 2010, 71(1): 104-109.
DOI:10.1016/j.phytochem.2009.09.032

摘要

Nine clerodane diterpenes, solidagoic acids C-I (1-7), cleroda-3,13(14)-dien-16,15:18,19-diolide (8) and cleroda-3,13(14)-dien-15,16:18,19-diolide (9) were isolated and characterised from the ethanol-ethyl acetate (1:1) extract of Solidago virgaurea. The structures were determined by NMR spectroscopic analysis. Several displayed moderate antibacterial activity against Staphylococcus aureus.

  • 出版日期2010-1