Utility of Pandemic H1N1 2009 Influenza Virus Recombinant Hemagglutinin Protein-Based Enzyme-Linked Immunosorbent Assay for Serosurveillance

作者：Arankalle V A^*; Virkar R G; Tandale B V; Ingle N B

来源：Clinical and Vaccine Immunology, 2010, 17(9): 1481-1483.

DOI：10.1128/CVI.00223-10

An enzyme-linked immunosorbent assay (ELISA) for the detection of IgG antibodies against the pandemic H1N1 2009 influenza A virus, employing a recombinant hemagglutinin protein of the virus, was compared to the hemagglutination inhibition (HI) test using 783 serum samples. The results showed a concordance of 98.4%, suggesting the utility of the ELISA in serosurveillance. Two hundred sixty-nine (100%) serum samples with an HI titer of >= 20 were ELISA reactive.

• 出版日期2010-9